Highly perturbed genes and hub genes associated with type 2 diabetes in different tissues of adult humans: a bioinformatics analytic workflowArticle Published on 2022-10-012022-11-16 Journal: Functional & integrative genomics [Category] meta-analysis, [키워드] analysis Apoptosis applied approach association bioinformatics cell type complex defined diabete diabetes Differential gene expression differentially expressed gene downregulated downstream analysis eligible etiology FIVE Gene Expression Gene Expression Omnibus Genes Genetic greater Highly perturbed genes hub gene hub genes identify insulin Kyoto Manifestations marker gene Meta-analysis metabolomics Microarray non-specific ontologies Pathogenesis pathophysiological pathway Pathways Perturbation profiles provided random effect significantly systematic review T2D tissue Type type 2 diabete type 2 diabetes. upregulated utility [DOI] 10.1007/s10142-022-00881-5 PMC 바로가기
Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learningResearch article Published on 2022-10-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] age and sex attribute bioinformatics chronic disease Comorbidity complex country COVID-19 COVID-19 disease severity data extraction Delta demonstrated Effect effort fixed GISAID heterogeneous include information Interpretation lack logistic regression models machine learning meta-analysis Metadata Mild Mutation obesity omicron outcome pandemic Patient Predictive random random effect reduction in Repository risk robust SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 spike protein sequence severe disease severity Spike protein submitted subset time-consuming training vaccination variant viral genome sequence viral genomics virus while [DOI] 10.1016/j.compbiomed.2022.105969 [Article Type] Research article
Does potential antibody-dependent enhancement occur during SARS-CoV-2 infection after natural infection or vaccination? A meta-analysisArticle Published on 2022-09-192022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] 95%CI acute respiratory syndrome ADE Analysis Antibody-dependent enhancement approach article Chinese clinical symptom Cochrane Library conducted coronavirus Coronavirus disease 2019 COVID-19 databases Direct disease severity Egger evaluated Final Health indicated Infection Infrastructure initial international public health Meta-analysis Methodological quality natural infection occur pandemic Perspective population level professionals protective factor Publication bia random effect Reinfection risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine Science searched severe COVID-19 severity of COVID-19 SinoMed vaccination vaccination. Vaccine was used [DOI] 10.1186/s12879-022-07735-2 PMC 바로가기
Effectiveness of BBV152/Covaxin and AZD1222/Covishield vaccines against severe COVID-19 and B.1.617.2/Delta variant in India, 2021: a multi-centric hospital-based case-control studyResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] 95% confidence interval adjusted odds ratio AZD1222/Covishield BBV152/Covaxin calculate case-control study Complete confounders Control control patients country Coverage COVID-19 negative COVID-19 vaccines Critical Delta delta variant dose effective Effectiveness enrolled Escalation estimate highest hospitals India individual introduced logistic regression model mitigate objective pandemic random effect reduce Result second wave severe COVID-19 severe COVID-19 patients vaccination Vaccine vaccine dose variant with COVID-19 [DOI] 10.1016/j.ijid.2022.07.033 [Article Type] Research article
Influencing Factors of High PTSD Among Medical Staff During COVID-19: Evidences From Both Meta-analysis and Subgroup AnalysisReview article Published on 2022-09-012022-10-05 Journal: Safety and Health at Work [Category] 진단, [키워드] 95% CI Analysis article Better carried conducted Corona COVID-19 COVID-19 symptoms cross-sectional study database disorder Factor Health care Health care worker health department identify Infection Isolation knowledge medical staff mental illness Meta-analysis Nurse Nurses outcome Post-traumatic stress disorder Prevalence preventive measure PTSD public health random effect Result risk risk factor searched sensitivity analysis Seven Stress subgroup analysis systematic review women [DOI] 10.1016/j.shaw.2022.06.003 [Article Type] Review article
The risk of contracting SARS-CoV-2 or developing COVID-19 for people with cancer: A systematic review of the early evidenceSARS-CoV-2에 감염되거나 암에 걸린 사람에게 COVID-19가 발병할 위험: 초기 증거에 대한 체계적인 검토Review Published on 2022-09-012022-09-12 Journal: Journal of cancer policy [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] addition age analysis article articles Cancer cancer type clinician Comorbidities conducted Contact COVID-19 COVID-19 incidence COVID-19 vaccine database develop Diagnosis diagnosis of COVID-19 Evidence Haematological cancer Health Service high risk Immunocompromise individuals infected with SARS-CoV-2 infection risk lower risk measure methodological limitations Neoplasms Odds ratio Patient peer-reviewed performed positive Positive test primary endpoint Protective quantitative synthesis random random effect reported risk risk of bia SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2. Sex suggested susceptibility systematic review the Newcastle-Ottawa Scale Treatment vaccination virus while [DOI] 10.1016/j.jcpo.2022.100338 PMC 바로가기 [Article Type] Review
Remdesivir for the treatment of COVID-19: a systematic review and meta-analysisReview article Published on 2022-09-012022-10-05 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 임상, 치료법, [키워드] 95% CI assessment Bayesian benefit clinically conducted coronavirus COVID-19 criteria eight eligibility criteria evaluate Hospitalized hospitalized patient Inpatient mechanical ventilation Meta-analysis Mortality Neutral objective oxygen Oxygen requirements participant Participants Patient patients with COVID-19 performed Placebo Primary outcome Probability random effect randomized trials recommendation reduce reduced Remdesivir requiring supplemental oxygen Result risk risk of bia risk reduction searched Standard of care stratified supplemental oxygen systematic review the patient therapy Treatment with COVID-19 World Health Organization [DOI] 10.1016/j.cmi.2022.04.018 [Article Type] Review article
The effect of influenza vaccine in reducing the severity of clinical outcomes in patients with COVID-19: a systematic review and meta-analysis Research Published on 2022-08-222022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] 95% CI 95% confidence interval Admission Analysis CIs Clinical outcome clinical outcomes COVID-19 COVID-19 pandemic COVID-19 patient database Evidence favor FIVE fixed group heterogeneity Hospital admission indicated Infection Influenza intensive care limitations mean difference mechanical ventilation Meta-analysis mortality rate no significant difference observational study outcomes Patient random effect recent reduce reducing reported Research risk searched severity severity of COVID-19 significantly lower statistically significant difference systematic review vaccination Vaccine [DOI] 10.1038/s41598-022-18618-6 [Article Type] Research
The Associations of Iron Related Biomarkers with Risk, Clinical Severity and Mortality in SARS-CoV-2 Patients: A Meta-AnalysisSARS-CoV-2 환자의 위험, 임상 중증도 및 사망률과 철분 관련 바이오마커의 연관성: 메타 분석Review Published on 2022-08-192022-09-11 Journal: Nutrients [Category] SARS, 바이오마커, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition article Biomarker calculation caused clinical coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 progression deaths disease Diseases eligible evaluate Evidence ferritin ferritin level ferritin levels hemoglobin heterogeneity indicate Infection iron Iron metabolism iron. magnitude mean difference Meta-analysis metabolism Mortality non-survivor Non-survivors Occurrence opposite Patient peer-reviewed Previous studies previous study progression random effect respiratory risk SARS-CoV-2 searched serum severe acute respiratory syndrome Coronavirus severity significantly lower SMD Survivors the disease TIBC was used Web of Science with COVID-19 [DOI] 10.3390/nu14163406 PMC 바로가기 [Article Type] Review
Is it safe and effective to administer COVID-19 vaccines during pregnancy? A systematic review and meta-analysisResearch article Published on 2022-08-012022-10-05 Journal: American journal of infection control [Category] SARS, 임상, [키워드] administer Admission adverse outcome adverse outcomes amniotic Analysis analyzed Blood consequence COVID-19 COVID-19 vaccination COVID-19 vaccine effective Effectiveness Efficacy evaluate fetal Future Hospitalization incidence Infection Meta-analysis Neonatal Neonatal COVID-19 objective observational study operative postpartum hemorrhage Pregnancy pregnant women Prevent Protective random effect Randomized Result Safe Safety SARS-CoV-2 infections searched stroke systematic review the vaccine Trial vaccination Vaccines vaginal delivery [DOI] 10.1016/j.ajic.2022.08.014 [Article Type] Research article